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The reactions the body triggers in times of pressure were first studied by the physiologist Hans Selye in the mid-thirties in his essay “General Adaptation Syndrome”. When we are confronted with a new situation, in Selye’s words ‘The Alarm Stage’, our brain receives information that is transmitted through our senses and analyses it, producing memories that we have ‘stored’ in our brain from previous similar experiences. If the evaluation is negative, it sends a signal that liberates the adrenaline hormones, putting our body in a state of alert. For a better understanding: The body has a special information system that relies on chemical messengers called hormones. These organic chemicals are made in ductless endocrine glands that pour their hormones into the blood. In most cases, the hormones then float to target organs where they turn biochemical reactions on or off. The major endocrine glands are the pituitary, the thyroid, the parathyroid, the pancreas, the adrenals, and the ovaries and testes. Hormones are also made in the stomach, the small intestine, and the kidneys. The pineal and the thymus glands possibly make them, too. The placenta of pregnant mammals has an endocrine function. It can make pituitary and ovarian hormones as well as a special one of its own.

The pituitary gland (also called the hypophysis) is a small, oval structure under the brain. It has two parts the anterior lobe (adenohypophysis) and the posterior lobe (neurohypophysis). In some animals, the adenohypophysis includes an intermediate lobe. The pituitary influences the activity of many other endocrine glands. Most of its hormones are made in its anterior lobe. Hence, the anterior pituitary is usually called the "master" gland of the body. Nearly all the anterior pituitary hormones act on specific tissues. Growth hormone, an exception, affects the body's overall growth processes.

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